1428450-95-6

  • Product Name：N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide
  • Molecular Formula：
  • Purity：99%
  • Molecular Weight：278.332
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Product Details

Factory Supply High Purity N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide, High Purity 99% 1428450-95-6 with Safe Delivery

  • Molecular Formula:C13H14N2O3S
  • Molecular Weight:278.332
  • Density:1.386±0.06 g/cm3(Predicted) 

N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide(Cas 1428450-95-6) Usage

Description

N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide is a white to pale yellow solid, existing in solid form at room temperature.

Uses

 N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide is a compound with substantial applications in the pharmaceutical and organic chemistry domains. This chemical is valuable in the development of pharmaceutical agents, particularly in the field of dermatology. It is used for its potential as a melanin synthesis inhibitor, making it a key component in the formulation of skin-lightening or anti-pigmentation products.

InChI:InChI=1S/C13H14N2O3S/c1-7(2)12(18)15-13-14-10(6-19-13)9-4-3-8(16)5-11(9)17/h3-7,16-17H,1-2H3,(H,14,15,18)

1428450-95-6 Relevant articles

COMBINATIONS OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES

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Paragraph 0058; 0060, (2016/02/10)

Disclosed are active ingredient combinat...

COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV-FILTER SUBSTANCES

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Paragraph 0080-0082, (2016/02/28)

Disclosed are active ingredient combinat...

COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND FRAGRANCES

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Paragraph 0060; 0062, (2016/02/12)

Disclosed are active ingredient combinat...

ALKYLAMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ALKYLAMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN

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, (2014/05/08)

Alkylamidothiazoles of general formula (...

1428450-95-6 Process route

2-methylpropionyl thiourea
6965-58-8

2-methylpropionyl thiourea

2-bromo-2',4'-bismethoxycarbonyloxyacetophenone
1428451-07-3

2-bromo-2',4'-bismethoxycarbonyloxyacetophenone

N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)isobutyramide
1428450-95-6

N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)isobutyramide

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / ethanol / 0.5 h / Reflux
2: sodium hydroxide; water / ethanol / 0.5 h / 20 °C
With water; sodium hydrogencarbonate; sodium hydroxide; In ethanol;
 
2-methylpropionyl thiourea; 2-bromo-2',4'-bismethoxycarbonyloxyacetophenone; With sodium hydrogencarbonate; In ethanol; for 0.5h; Reflux;
With sodium hydroxide; In ethanol; water; at 20 ℃; for 0.5h;
56 g
2-methylpropionyl thiourea; 2-bromo-2',4'-bismethoxycarbonyloxyacetophenone; With sodium hydrogencarbonate; In ethanol; for 0.5h; Reflux;
With water; sodium hydroxide; In ethanol; at 20 ℃; for 0.5h;
56 g
2-methylpropionyl thiourea; 2-bromo-2',4'-bismethoxycarbonyloxyacetophenone; With sodium hydrogencarbonate; In ethanol; for 0.5h; Reflux;
With water; sodium hydroxide; In ethanol; at 20 ℃; for 0.5h;
56 g
C<sub>17</sub>H<sub>18</sub>N<sub>2</sub>O<sub>7</sub>S

C17H18N2O7S

N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)isobutyramide
1428450-95-6

N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)isobutyramide

Conditions
Conditions Yield
With water; sodium hydroxide; In ethanol; at 20 ℃; for 0.5h;
56 g

1428450-95-6 Upstream products

  • 6965-58-8
    6965-58-8

    2-methylpropionyl thiourea

  • 1428451-07-3
    1428451-07-3

    2-bromo-2',4'-bismethoxycarbonyloxyacetophenone

  • 89-84-9
    89-84-9

    2',4'-dihydroxy-4-acetophenone

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